Before you even consider having a one night stand, make sure you are ready for it. Sometimes no sex is better than meaningless sex. You have to make sure the desire to have a fling is coming from a fun and confident place and not a sad, lonely place.
If you find someone fun to roll around with, try to do a little snooping before you go home with them. If you meet them out, try to do a quick Google search when they go to the bathroom. Ask their friend's some questions. You want to make sure that you aren't going to become the subject of the next episode of My Favorite Murder.
Find the person you want to sleep with before the beer goggles and not after. Then get a little tipsy and then go home with them. If you find them after the goggles kick in, it could end in a disaster.
Don't be a moron. Use protection. I don't care if they say that they just got tested and you just did too. YOU DON'T KNOW THEM! You don't want this night to cause any burning sensations in your no-no spots and you also don't want a little bun in the oven after a roll in the hay. Don't be a dummy and wrap it up.
You need to make sure that you are safe and aware of your surroundings, so don't get too smashed. A few drinks so you'll be a little tipsy is fine, but hammered is a bad idea. Also, please make sure you guard your drink. You never know who you are actually talking to. It's better to be safe than sorry.
Your bartender is good for more than just making drinks. When your potential one night stand isn't listening, ask your bartender what they think of them and the idea of going home with them. They will give you honest advice and tell you to either go for it or run and you should listen. A bartender has seen it all.
Don't bring them back to your place; go to theirs. You don't want them to see where you live and you also don't want to get stuck with them at your place. Go to theirs, do the deed and leave. You don't want to overstay your welcome.
If it goes well, make sure you have all of their information. This could be a potential booty call and you don't want to miss the opportunity. It the sex is good, keep in touch! You never know when you may need them.
Make sure you have your earrings, your underwear and your bra. You may never see this person again and you don't want to lose your favorite bra forever. Those earrings are worth more than that one night stand.
When it's all over, check in with yourself. Did that feel good or bad? Was it a healthy choice or was it something that was possibly not the best decision for you? You rule your life. Do whatever you want to do if it makes you feel good and never ever apologize for it.